A case of right Alzheimer’s disease
Early imaging studies found that a subgroup of patients with Alzheimer’s disease (AD) showed preponderant visuospatial impairments and consensual hypometabolism in the PET scan, especially prevalent at the right parietal region . The term right Alzheimer’s disease (RAD) was used to name this clinical and anatomical presentation of AD. However, the RAD syndrome has rarely been described in detail. Moreover, early cases of RAD seemed to share some features of the posterior cortical atrophy (PCA) syndrome of AD . More recently, the concept of RAD has been proposed by some authors when explaining the heterogeneity of the AD and the different forms animating this condition. In particular, Lam et al.  described the case of a woman with early-onset AD presenting with short-term memory deficits and difficulties at visually guided tasks; her symptoms seemed to be characterized by temporal and parietal cortical involvement, especially of the right parietal region. The...
KeywordsAlzheimer’s disease (AD) Variant of AD Left–right asymmetry Right AD (RAD) Visuospatial
Special thanks are due to the patient SR and her son for their long-standing cooperation in testing and clinical interviews. Moreover, we thank Luigi Flaminio Ghilardini a lot for his help in editing the digital figures.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
Statement of human and animal rights
The study has been approved by the institutional research committe of the Fondazione Ca' Granda and has been performed in accordance with the ethical standards of the Fondazione Ca' Granda and with the 1964 Helsinki Declaration and its later amendments.
Informed consent was obtained from all individual participants included in the study.