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Genetic and environmental relationships between eating behavior and symptoms of anxiety and depression

  • Yun-Mi Song
  • Kayoung LeeEmail author
  • Joohon Sung
Original Article

Abstract

Purpose

To assess gender-specific genetic and environmental correlations between depressive and anxiety symptoms, and concurrent and follow-up eating behavior in Korean twins and their family members.

Methods

Center for Epidemiological Studies Depression Scale and State-Trait Anxiety Inventory were used to measure depressive and anxiety symptoms in subjects. To assess concurrent and follow-up relationships of the symptoms with eating behavior domains (restrained, emotional, and external eating), the Dutch Eating Behavior Questionnaire was administered to 2359 subjects at baseline (men, 48.5%; 42.0 ± 12.7 years; monozygotic twins, 33.7%) and to 1169 subjects at follow-up (men, 45.9%; 44.9 ± 11.6 years; monozygotic twins, 41.0%). A mixed linear model and bivariate analysis were applied.

Results

After adjusting for age, twin and family effects, income, education, smoking status, alcohol use, exercise, and body mass index, depressive and anxiety symptoms were positively associated with concurrent and follow-up emotional and external eating, but not with restrained eating. The effect size of association with emotional eating increased in men in men over time, but decreased in women. Common genetic and environmental correlations showed a difference between genders, and their strength changed with time. Nevertheless, common genetic correlations were found between depressive and anxiety symptoms, and concurrent emotional eating, in both genders. There were common environmental correlations between anxiety symptoms, and concurrent restrained and emotional as well as follow-up emotional eating, in both genders.

Conclusions

There are similarities and differences in genetic and environmental relationships between depressive and anxiety symptoms and eating behaviors, based on gender and time of assessment.

Level of evidence

Level III, cohort study.

Keywords

Eating behavior Depressive symptoms Anxiety symptoms Genetic correlation Environmental correlation 

Notes

Acknowledgements

This work was supported by 2017 Inje University Busan Paik Hospital Research Grant.

Compliance with ethical standards

Conflict of interest

This work was supported by the 2016 Inje University Research Grant.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Family Medicine, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulRepublic of Korea
  2. 2.Department of Family Medicine, Busan Paik HospitalInje University College of MedicineBusanRepublic of Korea
  3. 3.Department of Epidemiology, School of Public Health and Institute of Health and EnvironmentSeoul National UniversitySeoulRepublic of Korea

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