Inpatient weight curve trajectory as a prognostic factor among adolescents with anorexia nervosa: a preliminary report

  • Adar Avnon
  • Naomi Orkaby
  • Arik Hadas
  • Uri Berger
  • Anat Brunstein Klomek
  • Silvana FennigEmail author
Original Article



To investigate the predictive value of weight restoration trajectories for relapse within the first year after discharge from inpatient treatment among adolescents with AN.


Forty four inpatient adolescents (5 boys, 39 girls) aged 11–18 (M 14.85, SD 1.87) diagnosed with anorexia were assessed at admission and discharge from a general hospital inpatient ward. Re-hospitalizations within 1 year of discharge were recorded. Factors assessed included 1/BMI at admission, 2/BMI at discharge, 3/percent from target weight (PFTW) at discharge, 4/length of hospitalization, and 5/a weight restoration trajectory measuring weight drops during inpatient weight restoration (rates of negative cubic variation in body weight (NCV).


Logistic regression indicated that negative cubic variation rates (NCV) predicted re-hospitalization. PFTW was found only marginally significant.


Variations in weight restoration during inpatient treatment may be used to identify patients at risk for relapse. NCV can alert clinicians to initiate early relapse prevention interventions before discharge.

Level of Evidence Level III, cohort study.


Eating disorders Inpatient treatment Adolescents Weight restoration Weight curve 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the official IRB Committee of the hospital and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Child and Adolescent Psychiatric Department, Schneider Children’s Medical Center, Faculty of Health SciencesBen-Gurion University of the NegevBeer ShevaIsrael
  2. 2.Joyce and Irving Goldman Medical SchoolBen-Gurion University of the NegevBeer ShevaIsrael
  3. 3.Child and Adolescent Psychiatric Department, Schneider Children’s Medical Center of IsraelAcademic College of Tel-Aviv YafoTel AvivIsrael
  4. 4.Child and Adolescent Psychiatric Department, Schneider Children Medical Center of Israel and Brill’s Mental Health CenterTel AvivIsrael
  5. 5.Department of Psychology and The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research CenterBar-Ilan UniversityRamat-GanIsrael
  6. 6.Child and Adolescent Psychiatric Department, Schneider Children’s Medical Center of IsraelPetach TikvahIsrael
  7. 7.School of Psychology, Interdisciplinary Center (IDC)HerzliyaIsrael
  8. 8.Sackler School of Medicine, Tel Aviv UniversityTel AvivIsrael

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