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Current Oral Health Reports

, Volume 4, Issue 2, pp 158–166 | Cite as

Periodontal Medicine—New Diagnostic Opportunities

  • Ricardo TelesEmail author
Systemic Diseases (M Bartold, section editor)
  • 97 Downloads
Part of the following topical collections:
  1. Topical Collection on Systemic Diseases

Abstract

Purpose of Review

We examined the literature on periodontal medicine to determine how this field has influenced the diagnosis of periodontal diseases and the search for biomarkers in oral fluids.

Recent Findings

Periodontal medicine has pushed the boundaries of biomarker discovery in oral fluids, where several analytes present in serum can be detected and potentially explored for the diagnosis of systemic conditions. The study of mechanisms linking oral and systemic diseases has also contributed to advances in our understanding of systemic modulation of the subgingival microenvironment and its effects on gingival crevicular fluid components and the local microbiota.

Summary

Recent technological advances in “omics” platforms allow us to examine concomitantly functional changes that occur in the host and the resident microbiota during disease processes. Integration of multi-omics data such as the one proposed by the Integrative Human Microbiome Project will afford new insights into the interplay between oral and systemic diseases.

Keywords

Periodontal diseases Systemic adverse outcomes Biomarkers Saliva Gingival crevicular fluid Microbiome 

Notes

Compliance with Ethical Standards

Conflict of Interest

The author declares that he has no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of PeriodontologyUNC School of DentistryChapel HillUSA
  2. 2.Department of Applied Oral SciencesForsyth InstituteCambridgeUSA

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