Biodentine™ material characteristics and clinical applications: a 3 year literature review and update
- 798 Downloads
Biodentine™ has frequently been acknowledged in the literature as a promising material and serves as an important representative of tricalcium silicate based cements used in dentistry.
To provide an update on the physical and biological properties of Biodentine™ and to compare these properties with those of other tricalcium silicate cements namely, different variants of mineral trioxide aggregate (MTA) such as ProRoot MTA, MTA Angelus, Micro Mega MTA (MM-MTA), Retro MTA, Ortho MTA, MTA Plus, GCMTA, MTA HP and calcium enriched mixture (CEM), Endosequence and Bioaggregate™.
A comprehensive literature search for publications from November 20, 2013 to November 20, 2016 was performed by two independent reviewers on Medline (PubMed), Embase, Web of Science, CENTRAL (Cochrane), SIGLE, SciELO, Scopus, Lilacs and clinicaltrials.gov. Electronic and hand search was carried out to identify randomised control trials (RCTs), case control studies, case series, case reports, as well as in vitro and animal studies published in the English language.
The enhanced physical and biologic properties of Biodentine™ could be attributed to the presence of finer particle size, use of zirconium oxide as radiopacifier, purity of tricalcium silicate, absence of dicalcium silicate, and the addition of calcium chloride and hydrosoluble polymer. Furthermore, as Biodentine™ overcomes the major drawbacks of MTA it has great potential to revolutionise the different treatment modalities in paediatric dentistry and endodontics especially after traumatic injuries. Nevertheless, high quality long-term clinical studies are required to facilitate definitive conclusions.
KeywordsBiodentine™ Tricalcium silicate
The authors declare that no funding was received for this review.
Compliance with ethical standards
Conflict of interest
The research group received material support from Septodont, Paris, France for educational programmes intended for general dentists.
- Bani M, Sungurtekin-Ekci E, Odabas ME. Efficacy of Biodentine as an apical plug in nonvital permanent teeth with open apices: an in vitro study. Biomed Res Int. 2015;2015(2015):4.Google Scholar
- Bolhari B, Ashofteh Yazdi K, Sharifi F, Pirmoazen S. Comparative scanning electron microscopic study of the marginal adaptation of four root-end filling materials in presence and absence of blood. J Dent (Tehran). 2015;12:226–34.Google Scholar
- Deepa VL, Dhamaraju B, Bollu IP, Balaji TS. Shear bond strength evaluation of resin composite bonded to three different liners: TheraCal LC, Biodentine, and resin-modified glass ionomer cement using universal adhesive: An in vitro study. J Conserv Dent. 2016;19:166–70.PubMedPubMedCentralCrossRefGoogle Scholar
- Govindaraju L, Neelakantan P, Gutmann JL (2016) Effect of root canal irrigating solutions on the compressive strength of tricalcium silicate cements. Clin Oral Investig [Epub ahead of print].Google Scholar
- Kucukkaya S, Gorduysus MO, Zeybek ND, Muftuoglu SF. In vitro cytotoxicity of calcium silicate-based endodontic cement as root-end filling materials. Scientifica. 2016;2016(2016):5.Google Scholar
- Li X, Yoshihara K, De Munck J, et al. (2016) Modified tricalcium silicate cement formulations with added zirconium oxide. Clin Oral Investig [Epub ahead of print].Google Scholar
- Mandava P, Bolla N, Thumu J, Vemuri S, Chukka S. Microleakage evaluation around retrograde filling materials prepared using conventional and ultrasonic techniques. J Clin Diagn Res. 2015;9:43–6.Google Scholar
- Nadig PP, Agrawal IS, Agrawal VS, Srinivasan SC. Palato-radicular groove: a rare entity in maxillary central incisor leading to endo-perio lesion. J Clin Diagn Res. 2016;10:14–5.Google Scholar
- Niranjani K, Prasad MG, Vasa AA, et al. Clinical evaluation of success of primary teeth pulpotomy using mineral trioxide aggregate((R)), laser and Biodentine(TM)—an in vivo study. J Clin Diagn Res. 2015;9:35–7.Google Scholar
- Poggio C, Ceci M, Beltrami R, et al. Biocompatibility of a new pulp capping cement. Ann Stomatol (Roma). 2014b;5:69–76.Google Scholar
- Raju VG, Venumbaka NR, Mungara J, et al. Comparative evaluation of shear bond strength and microleakage of tricalcium silicate-based restorative material and radioopaque posterior glass ionomer restorative cement in primary and permanent teeth: an in vitro study. J Indian Soc Pedod Prev Dent. 2014;32:304–10.PubMedCrossRefGoogle Scholar
- Silva EJ, Carvalho NK, Zanon M, et al. Push-out bond strength of MTA HP, a new high-plasticity calcium silicate-based cement. Braz Oral Res. 2016a;30(1). https://doi.org/10.1590/1807-3107BOR-2016.vol30.0084
- Soni HK. Biodentine pulpotomy in mature permanent molar: a case report. J Clin Diagn Res. 2016;10:9–11.Google Scholar
- Soundappan S, Sundaramurthy JL, Raghu S, Natanasabapathy V. Biodentine versus mineral trioxide aggregate versus intermediate restorative material for retrograde root end filling: an invitro study. J Dent (Tehran). 2014;11:143–9.Google Scholar