Prevalence of oral lichen planus in Iranian children and adolescents: a 12-year retrospective study
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To investigate the prevalence of oral lichen planus in patients younger than 18 years, referred to a dermatology centre in Iran during 2002–2014. Lichen planus is a chronic inflammatory, immune-mediated disease that could affect the oral mucosa and is a pre-cancerous condition. The disease usually develops in middle age with female predominance and is rare in children.
In this retrospective study, cases with definitive histopathologic diagnosis of lichen planus, over a 12-year period from 2002 to 2014 from a dermatologic hospital archive were evaluated. The prevalence of both cutaneous and oral lichen planus, the male:female ratio and site of involvement were calculated using SPSS version 21.
Thirty-six of 564 patients younger than 18 years old diagnosed with lichen planus. Two females (0.4%) had oral lichen planus. One patient had erosive, and one had bullous, oral lichen planus.
Oral lichen planus had a very low frequency in Iranian population younger than 18 years old, identifying these patients is recommended for long-term follow-up.
KeywordsOral Lichen planus Prevalence Children Adolescent
The authors would like to thank Dr. Bakhshi from Shahid Beheshti University of Medical Science and Estie Kruger of the University of Western Australia for assistance and advice with this project.
Compliance with ethical standards
There is no source of funding for this study.
Conflict of interest
There is no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was based on archives of the hospital. We confirm that patient information remained confidential and data were anonymised and non-identifiable prior to analysis.
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