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European Archives of Paediatric Dentistry

, Volume 18, Issue 3, pp 215–218 | Cite as

A new emerging oral infection: Raoultella planticola in a boy with haematological malignancy

  • E. BardelliniEmail author
  • F. Amadori
  • R. F. Schumacher
  • I. Foresti
  • A. Majorana
Case Report

Abstract

Background

Oral mucositis is a common complication in pediatric cancer patients, affecting up to 80% of children. Due to neutropenia and disruption of the mucosal barrier, chemotherapy-induced oral mucositis is often complicated by super-infections.

Case report

A 16-years old male with stage 3 Burkitt’s lymphoma developed chemotherapy induced oral mucositis grade 3 (according to WHO scale). Ulcers were quickly growing (reaching a maximum diameter of 3 cm) and became greyish in colour, resulting in dysphagia and pain. A swab of the lesions was taken and microbiological tests were performed. The sample grew for Raoultella planticola, an encapsulated Gram-negative bacterium whose full pathogenic potential still needs to be defined. Treatment: The patient received antibiotic combination therapy with Amikacin and Ceftazidime for 8 days. Complete healing of the lesions and resolution of the symptoms were reached and he completed his antineoplastic therapy without further complications. Follow-up: Twelve months after the infection, he is alive and well, with no oral complaints.

Conclusion

This is the first report of a Raoultella planticola infection in a patient with chemotherapy induced oral mucositis. This type of infection must be added to the list of organisms to be considered when caring for these patients.

Keywords

Oral ulcer Infection Anti-neoplastic agents 

Notes

Compliance with ethical standards

Conflict of interest

The Authors declare that they have no conflict of interest.

Ethical standard

All procedures performed in this study were in accordance with the ethical standards of the Declaration of Helsinki.

Informed consent

Informed consent from the patient’s parents for the publication of the case was taken.

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Copyright information

© European Academy of Paediatric Dentistry 2017

Authors and Affiliations

  • E. Bardellini
    • 1
    Email author
  • F. Amadori
    • 1
  • R. F. Schumacher
    • 2
  • I. Foresti
    • 3
  • A. Majorana
    • 1
  1. 1.Department Oral Medicine and Paediatric DentistryDental Clinic, University of BresciaBresciaItaly
  2. 2.Paediatric Haematology-Oncology UnitSpedali Civili di BresciaBresciaItaly
  3. 3.Microbiology DepartmentSpedali Civili di BresciaBresciaItaly

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