A new emerging oral infection: Raoultella planticola in a boy with haematological malignancy
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Oral mucositis is a common complication in pediatric cancer patients, affecting up to 80% of children. Due to neutropenia and disruption of the mucosal barrier, chemotherapy-induced oral mucositis is often complicated by super-infections.
A 16-years old male with stage 3 Burkitt’s lymphoma developed chemotherapy induced oral mucositis grade 3 (according to WHO scale). Ulcers were quickly growing (reaching a maximum diameter of 3 cm) and became greyish in colour, resulting in dysphagia and pain. A swab of the lesions was taken and microbiological tests were performed. The sample grew for Raoultella planticola, an encapsulated Gram-negative bacterium whose full pathogenic potential still needs to be defined. Treatment: The patient received antibiotic combination therapy with Amikacin and Ceftazidime for 8 days. Complete healing of the lesions and resolution of the symptoms were reached and he completed his antineoplastic therapy without further complications. Follow-up: Twelve months after the infection, he is alive and well, with no oral complaints.
This is the first report of a Raoultella planticola infection in a patient with chemotherapy induced oral mucositis. This type of infection must be added to the list of organisms to be considered when caring for these patients.
KeywordsOral ulcer Infection Anti-neoplastic agents
Compliance with ethical standards
Conflict of interest
The Authors declare that they have no conflict of interest.
All procedures performed in this study were in accordance with the ethical standards of the Declaration of Helsinki.
Informed consent from the patient’s parents for the publication of the case was taken.
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