European Archives of Paediatric Dentistry

, Volume 14, Issue 4, pp 233–238 | Cite as

Aetiology of molar–incisor hypomineralisation (MIH) in Brazilian children

  • J. F. Souza
  • F. Jeremias
  • C. M. Costa-Silva
  • L. Santos-Pinto
  • A. C. C. Zuanon
  • R. C. L. CordeiroEmail author
Original Scientific Article



To determine the potential aetiological factors related to molar–incisor hypomineralisation (MIH) in Brazilian children.


A total of 1,151 children aged 7–12 years (mean 8.86 ± 1.28), born and living in the urban area of Araraquara, Brazil, were examined by two examiners evaluating the presence of MIH according to criteria suggested by the European Academy of Paediatric Dentistry (2003). Their mothers completed a structured questionnaire about medical history, from pregnancy to the first 3 years of the children’s life. Descriptive analyses of data and odds ratios (OR) with 95 % test-based confidence intervals (CI) were estimated. Chi-square test was used to evaluate the differences between groups.


The prevalence of MIH in the children was 12.3 %. The interviewing response rate was 90.4 %. The prevalence of miscarriage history (25 vs. 15.4 %; OR = 1.21; 95 % CI 0.30–4.92) and occurrence of anaemia (23 vs. 12.4 %; OR = 2.07; 95 % CI 0.50–8.63) were higher in mothers from MIH group than those from non-MIH group. However, these associations were not statically significant. In the children’s medical history, rhinitis, bronchitis (56.5 vs. 52.5 %; OR = 1.17; 95 % CI 0.82–1.68), and high fever (20.4 vs. 18.2 %; OR = 1.14; 0.73–1.76) were more prevalent in MIH group, but there were no significant differences between the groups (p > 0.05).


No possible aetiological factor investigated was associated with MIH. Prospective studies are needed to define the aetiological factors involved with MIH.


Epidemiology Aetiology Molar–incisor hypomineralisation 



This study was supported by FAPESP—Grant Master (Proc.: 2008/03247-9) and CNPq—Universal Call (Proc.: 473126/2008 7).


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Copyright information

© European Academy of Paediatric Dentistry 2013

Authors and Affiliations

  • J. F. Souza
    • 1
  • F. Jeremias
    • 1
  • C. M. Costa-Silva
    • 2
  • L. Santos-Pinto
    • 1
  • A. C. C. Zuanon
    • 1
  • R. C. L. Cordeiro
    • 1
    Email author
  1. 1.Department of Paediatric Dentistry and OrthodonticsAraraquara Dental School; Univ Estadual Paulista (UNESP)AraraquaraBrazil
  2. 2.Division of Health Education and Health Promotion, Department of Community Dentistry, Piracicaba Dental SchoolUniversity of Campinas UNICAMPPiracicabaBrazil

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