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High Blood Pressure & Cardiovascular Prevention

, Volume 26, Issue 6, pp 493–499 | Cite as

Evaluation of Unattended Automated Office, Conventional Office and Ambulatory Blood Pressure Measurements and Their Correlation with Target Organ Damage in an Outpatient Population of Hypertensives: Study Design and Methodological Aspects

  • Costantino MancusiEmail author
  • Francesca Saladini
  • Giacomo Pucci
  • Fabio Bertacchini
  • Valeria Bisogni
  • Rosa Maria Bruno
  • Giulia Rivasi
  • Alessandro Maloberti
  • Maria Virginia Manzi
  • Martina Rosticci
  • Silvia Monticone
  • Martina de Feo
  • Rita Del Pinto
  • Giulio Geraci
  • Grazia Canciello
  • Martino Pengo
  • Gianfranco Parati
  • Proposal of Young Investigator Group of the Italian Hypertension Society (Società Italiana dell’Ipertensione Arteriosa)
Original article
  • 41 Downloads

Abstract

Accurate measurement of blood pressure (BP) has a pivotal role in the management of patients with arterial hypertension. Recently, introduction of unattended office BP measurement has been proposed as a method allowing more accurate management of hypertensive patients and prediction of hypertension-mediated target organ damage (HMOD). This approach to BP measurement has been in particular proposed to avoid the white coat effect (WCE), which can be easily assessed once both attended and unattended BP measurements are obtained. In spite of its interest, the role of WCE in predicting HMOD remains largely unexplored. To fill this gap the Young Investigator Group of the Italian Hypertension Society (SIIA) conceived the study “Evaluation of unattended automated office, conventional office and ambulatory blood pressure measurements and their correlation with target organ damage in an outpatient population of hypertensives”. This is a no-profit multicenter observational study aiming to correlate attended and unattended BP measurements for quantification of WCE and to correlate WCE with markers of HMOD, such us left ventricular hypertrophy, left atrial dilatation, and peripheral atherosclerosis. The Ethical committee of the Federico II University hospital has approved the study.

Keywords

White coat effect Left ventricular hypertrophy Ankle brachial index Echocardiography 

Notes

Acknowledgements

We thank Prof. Giovanni de Simone for critical revision and improvement of the paper.

Compliance with Ethical Standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee (Ethical Committee authorities of Federico II University of Naples, approval number: 338/18.) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Italian Society of Hypertension 2019

Authors and Affiliations

  • Costantino Mancusi
    • 1
    Email author
  • Francesca Saladini
    • 2
  • Giacomo Pucci
    • 3
  • Fabio Bertacchini
    • 4
  • Valeria Bisogni
    • 5
  • Rosa Maria Bruno
    • 6
  • Giulia Rivasi
    • 7
  • Alessandro Maloberti
    • 8
  • Maria Virginia Manzi
    • 1
  • Martina Rosticci
    • 9
  • Silvia Monticone
    • 10
  • Martina de Feo
    • 11
  • Rita Del Pinto
    • 11
  • Giulio Geraci
    • 12
  • Grazia Canciello
    • 13
  • Martino Pengo
    • 14
  • Gianfranco Parati
    • 15
    • 16
  • Proposal of Young Investigator Group of the Italian Hypertension Society (Società Italiana dell’Ipertensione Arteriosa)
  1. 1.Department of Advanced Biomedical Science and Hypertension Research CenterFederico II University of NaplesNaplesItaly
  2. 2.UO Cardiologia, PO CittadellaPaduaItaly
  3. 3.Department of MedicineUniversity of PerugiaPerugiaItaly
  4. 4.Unit of Internal MedicineTerni University HospitalTerniItaly
  5. 5.Department of Clinic Sciences and Translational Medicine, Unit of Secondary Arterial Hypertension“Sapienza” University of RomeRomeItaly
  6. 6.Department of Experimental Clinical MedicineUniversity of PisaPisaItaly
  7. 7.Department of Geriatrics and Geriatric Intensive Care Unit, Hypertension CenterCareggi Hospital and University of FlorenceFlorenceItaly
  8. 8.School of Medicine and SurgeryUniversity of Milano-BicoccaMilanItaly
  9. 9.Medicine and Surgery Sciences DepartmentAlma Mater Studiorum University of BolognaBolognaItaly
  10. 10.Division of Internal Medicine and Hypertension Unit, Department of Medical SciencesUniversity of TorinoTurinItaly
  11. 11.Department of Life, Health and Environmental SciencesUniversity of L’AquilaL’AquilaItaly
  12. 12.Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical SpecialtiesUniversity of PalermoPalermoItaly
  13. 13.Echocardiography Core LAB, Hypertension Research CenterFederico II University of NaplesNaplesItaly
  14. 14.Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, Sleep Disorder CentreSan Luca HospitalMilanItaly
  15. 15.Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCSSan Luca HospitalMilanItaly
  16. 16.Department of Medicine and SurgeryUniversity of Milano-BicoccaMilanItaly

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