Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension
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Over the last decades, blood pressure (BP) levels have been measured at brachial level by conventional sphygmomanometers and, more recently, by validated and accurate automated devices. This method has been systematically applied in observational studies and in large randomized controlled clinical trials for both diagnostic and therapeutic purposes in the clinical management of essential hypertension. As an example, data from the Framingham cohort of individuals have demonstrated the strong and independent relationship between BP levels, mostly systolic, and increased risk of major cardiovascular outcomes, including myocardial infarction, stroke, renal disease, congestive heart failure and cardiovascular death . Similar findings have been observed in various epidemiological surveys in almost all countries all over the world, including Italy . On the other hand, pharmacological and non pharmacological interventions aimed at reducing high peripheral (brachial) BP levels have...
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Conflict of interest
Authors have no conflict of interest to disclose.
This article does not contain data derived by any current studies with human participants performed by any of the authors. The clinical studies mentioned were provided with specific ethical approval.
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