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Liquid Biopsy Applications in the Clinic

Abstract

The global liquid biopsy industry is expected to exceed $US5 billion by 2023. One application of liquid biopsy technology is the diagnosis of disease using biomarkers found in blood, urine, stool, saliva, and other biological samples from patients. These biomarkers could be DNA, RNA, protein, or even a cell. More recently, the use of cell-free DNA from plasma is emerging as an important minimally invasive tool for clinical diagnosis. The development of technology has increased the diversity of its application. Here, we discuss how liquid biopsies have been used in the clinic, and how personalized medicine are likely to use liquid biopsies in the near future.

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Correspondence to Tao Yu or Yu Zhu or Jian Chen.

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Conflict of interest

Dake Chen, Tao Xu, Shubin Wang, Howard Chan, Tao Yu, Yu Zhu, and Jian Chen have no conflicts of interest that are directly relevant to the content of this review/study.

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Chen, D., Xu, T., Wang, S. et al. Liquid Biopsy Applications in the Clinic. Mol Diagn Ther (2020) doi:10.1007/s40291-019-00444-8

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