Comment on: “Cardiorespiratory Fitness in Childhood and Adolescence Affects Future Cardiovascular Risk Factors: A Systematic Review of Longitudinal Studies”
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We would like to congratulate Mintjens et al. on their systematic review ‘Cardiorespiratory Fitness in Childhood and Adolescence Affects Future Cardiovascular Risk Factors: A Systematic Review of Longitudinal Studies’, published recently in Sports Medicine . The article provided valuable recommendations for future work, including recommendations to reduce heterogeneity between studies, and an insightful reflection on the intricate relationship between physical activity, cardiorespiratory fitness and adiposity. However, we wish to highlight certain nuances that we feel are of importance when interpreting the results of this review, as well as observational cohort studies in general.
The utility of quality-scores/checklists for evaluating potential threats (biases) to scientific conclusions from systematic reviews is debatable . Mintjens et al.  included two different systems for rating articles in their review. The STROBE quality assessment was used to rate...
Compliance with ethical standards
No sources of funding were used to assist in the preparation of this letter.
Conflict of interest
Jakob Tarp, Knut Eirik Dalene, Jostein Steene-Johannessen and Ulf Ekelund declare that they have no conflicts of interest relevant to the content of this letter.
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