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, Volume 1766, Issue 1, pp 210–210 | Cite as


Renal insufficiency and acute amoebic encephalitis due to Acanthamoeba species: case report
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A man in his mid 70s' [exact age at reactions onset not stated] developed renal insufficiency and acute amoebic encephalitis during treatment with mycophenolate, prednisone and tacrolimus following an allogeneic peripheral blood haematopoietic stem-cell transplant [HSCT; not all dosages stated, routes not stated].

The man had a history of hyperlipidaemia, hypertension, stent placement and coronary artery disease, which required angioplasty. Following treatment with fludarabine, busulfan and antithymocyte globulin [anti-thymocyte globulin], he had received an allogeneic peripheral blood HSCT for acute myelogenous leukaemia. He started receiving prednisone and tacrolimus for prevention of graft-versus-host disease (GVHD) after transplantation. Also, he started receiving...


  1. Molina A, et al. Acute amebic encephalitis in an allogeneic hematopoietic stem-cell transplant recipient: Still an overlooked diagnosis. Infectious Diseases in Clinical Practice 27: 188-190, No. 4, Jul 2019. Available from: URL: - USA

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© Springer International Publishing AG 2019

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