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In a case series, a 34-year-old woman developed Parvovirus B19 infection-related pure red blood cell aplasia (PRCA) and lower urinary tract infection, and a 30-year-old man developed PRCA during immunosuppressive treatment with ciclosporin, mycophenolate mofetil and tacrolimus [dosages, routes and duration of treatments to reaction onsets not stated].
Case 1: A 34-year-old woman, who had chronic kidney disease secondary to chronic glomerulonephritis of unknown origin, had undergone second kidney transplantation in August 2008. Her immunosuppressive treatment included ciclosporin [cyclosporine-A], mycophenolate mofetil and tacrolimus. One month after transplantation, her haemoglobin was 12 g/dL, creatinine level was 1.0 mg/dL and tacrolimus level was 15.3 ng/dL. The haemoglobin level reduced after 4 months post-transplantation. PRCA was suspected. Her mycophenolate mofetil dose was reduced to 1g every 24h. Further reduction of the haemoglobin level was noted during the next 4 weeks. Her...
- Pabisiak K, et al. Pure Red Cell Aplasia After Kidney Transplantation: Parvovirus B19 Culprit or Coincidence? Annals of Transplantation 24: 123-131, 5 Mar 2019. Available from: URL: http://doi.org/10.12659/AOT.913663 - Poland