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In a case series, four girls aged 8 week−8 month were described, who developed sleep disturbances, loose stools, diarrhoea, worsening of reflux or sleep disorders during treatment with propranolol. Out of these 4 girls, two girls also developed night terrors, worsening of reflux or sleep disturbances during treatment with propranolol [Hemangeol], two girls developed loose stools, gas, persistent sleep issues or vomiting during treatment with atenolol [routes not stated; not all times to reactions onsets and outcomes stated].
Patient 1: This report describes an approximately 8-week-old girl, who developed sleep disturbances and loose stools during treatment with propranolol. Additionally, she developed loose stools and gas during treatment with atenolol for infantile haemangioma: The girl presented with various symptoms at the age of 6 weeks and was diagnosed with infantile haemangioma. She started receiving propranolol 1 mg/kg/day at 1st week and 2 mg/kg/day at 2nd week. At the week 2...
- Gumina ME, et al. Atenolol as an alternative to propranolol for the management of sleep disturbances in the treatment of infantile hemangiomas. Pediatric Dermatology 36: 556-557, No. 4, Jul-Aug 2019. Available from: URL: http://doi.org/10.1111/pde.13839 - USA