Reactions Weekly

, Volume 1761, Issue 1, pp 310–310 | Cite as


Leptospirosis leading to pulmonary haemorrhage syndrome: case report
Case report
Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A 29-year-old man developed leptospirosis leading to pulmonary haemorrhage syndrome during treatment with prednisolone for lumbar disc prolapse.

The man had travelled to Indonesia for 3 weeks, where he was involved in trekking in the rainforest and swimming in fresh water pools. He received oral prednisolone 25mg daily for 5 days because of suspected lumbar disc prolapse until a few days before departure to Indonesia. In <24 hours following his return from Indonesia, he presented to the emergency room with headache, diarrhoea, chills, fever and myalgia, which lasted for <2 days. He experienced similar symptoms 8 days previously. At first presentation, heart rate was 109/minute, RR was 18/minute, peripheral oxygen saturation 100%, BP was 118/67mm Hg and body temperature was...


  1. Schonfeld A, et al. Severe pulmonary haemorrhage syndrome in leptospirosis in a returning traveller. Infection 47: 125-128, No. 1, Feb 2019. Available from: URL: - Germany

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© Springer International Publishing AG 2019

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