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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 60-year-old woman experienced worsening of small bowel obstruction following administration of barium sulphate during small bowel series. The barium sulfate was administered despite it was contraindicated in the setting of small bowel obstruction.
The woman, who had a history of Parkinson's disease, Sjogren's disease, gastro-oesophageal reflux disease, breast cancer, constipation, and multiple abdominal surgeries, presented to the emergency department (ED) with a 1 day history of crampy epigastric pain, bloating nausea and diarrhoea. Physical examination revealed epigastric tenderness on palpation, with normal bowel sounds and no guarding or distention. Abdominal and pelvic contrast CT scans revealed mildly distended loops of colon and small bowel, which was considered...
- Reid WL, et al. Small bowel obstruction exacerbated by barium sulfate administration. Human Pathology: Case Reports 17: Sep 2019. Available from: URL: http://doi.org/10.1016/j.ehpc.2019.200315 - USA