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Reactions Weekly

, Volume 1760, Issue 1, pp 23–23 | Cite as

Antibacterials

Various toxicities: 6 case reports
Case report
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Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a study of 387 patients, who underwent lung transplantation between 1 January 2010 and 1 April 2018, six patients (five females and one male) aged 16−63 years were described, who experienced nausea due to tigecycline (1 patient), ototoxicity due to amikacin and neuropathy due to linezolid (1 patient), nephrotoxicity due to cefoxitin (1 patient), nephrotoxicity due to both, cefoxitin and amikacin, as well as ototoxicity due to amikacin (1 patient) nephrotoxicity due to both, cefoxitin and amikacin, as well as ototoxicity (near complete sensorineural hearing loss) due to amikacin or ototoxicity due to amikacin and neuropathy due to tedizolid (1 patient), while being treated for pre‐transplant Mycobacterium abscessus pulmonary infections [not all routes stated; times to...

Reference

  1. Perez AA, et al. Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience. Transplant Infectious Disease 21: e13084, No. 3, Jun 2019. Available from: URL: http://doi.org/10.1111/tid.13084 - USA

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© Springer International Publishing AG 2019

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