Reactions Weekly

, Volume 1756, Issue 1, pp 38–38 | Cite as


Severe spontaneous non-cerebral bleeding: 25 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a retrospective study of 44 patients, 25 patients [14 women and 11 men] aged 50−92 years were described, who developed severe spontaneous non-cerebral haemorrhage during treatment with acenocoumarol, aspirin [Salospir][acetylsalicylic acid], clopidogrel, prasugrel, rivaroxaban, ticagrelor and warfarin [routes and duration of treatments to reactions onsets not stated; not all dosages and outcomes stated] as antithrombotic therapy.

Out of 44 patients, 19 patients were enrolled in endovascular treatment (EVT) group. Out of 19 patients, 7 patients had a history of major ischaemic stroke, atrial fibrillation, coronary artery disease, hypertension, myocardial infarction, heart failure, valvular heart disease, acute renal failure, urinary tract infection, urinary bladder rupture,...


  1. Spiliopoulos S, et al. Incidence and endovascular treatment of severe spontaneous non-cerebral bleeding: a single-institution experience. European Radiology 29: 3296-3307, No. 6, Jun 2019. Available from: URL: - Greece

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© Springer International Publishing AG 2019

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