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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a case report, two women, aged 83−87 years, were described, who developed intracranial cyst following treatment with gelatin/thrombin for haemostasis [durations of treatments to reactions onsets not stated].
Case 1: The 83-year-old woman initially presented with dizziness, nausea, vomiting and headache. She was sent to the emergency department of hospital in Taiwan. Her Glasgow Coma Scale (GCS) was E1M2V1 with bilaterally dilated pupils. Brain CT revealed right parieto-occipital intracranial haemorhhage (ICH) and subdural haematoma with a 2.2cm midline shift. She underwent emergent right fronto-temporo-parietal de-compressive craniectomy and subdural haematoma removal. For haemostasis, intraoperative topical gelatin/thrombin [FloSeal] was used in ICH cavity [dosage not stated...
- Ho M-Y, et al. Hemostatic Thrombin-Gelatin Matrix-Related Intracranial Cyst Formation. World Neurosurgery 126: 475-480, Jun 2019. Available from: URL: https://doi.org/10.1016/j.wneu.2019.03.030 - Taiwan