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, Volume 1747, Issue 1, pp 37–37 | Cite as

Antineoplastics

Severe interstitial lung damage secondary to interstitial lung diseases: 3 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a study, a 72-year-old man developed severe interstitial lung damage secondary to drug-induced interstitial lung disease (DILD) and he eventually died due to radiation recall pneumonitis following treatment with carboplatin and pemetrexed for epitheliomorphic mesothelioma, a 63-year-old man died due to severe pulmonary fibrosis secondary to DILD following treatment with cisplatin and gemcitabine for lung adenocarcinoma, and a 72-year-old man died due to severe interstitial lung damage secondary to DILD following treatment with carboplatin, vinorelbine, nivolumab and docetaxel for squamous cell laryngeal carcinoma [routes and dosages not stated].

Case 1: A 72-year-old man was diagnosed with epitheliomorphic mesothelioma in May 2016 and underwent atypical resection of the upper...

Reference

  1. Bargagli E, et al. Fibrotic lung toxicity induced by cytotoxic drugs, radiation and immunotherapy in patients treated for lung cancer. Monaldi Archives for Chest Disease 88: 17-20, No. 2, Jan 2018. Available from: URL: http://doi.org/10.4081/monaldi.2018.917 - ItalyCrossRefGoogle Scholar

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© Springer International Publishing AG 2019

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