- 50 Downloads
An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a retrospective case study of patients identified via pharmacy records as receiving cidofovir between 2008 and 2016, five men aged 30−82 years were described, who developed adenovirus (ADV) disease following treatment with mycophenolate mofetil, sirolimus, tacrolimus or prednisone for immunosuppression. Additionally, two of these five men also developed retinal tubular acidosis or iritis following treatment with cidofovir for ADV disease [duration of treatments to reaction onsets not stated; not all routes, dosages and outcomes stated].
Patient 1: An 82-year-old man developed ADV disease following treatment with tacrolimus and mycophenolate mofetil for immunosuppression. He also developed renal tubular acidosis type 2 following treatment with cidofovir for disseminated...