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In a case series of patients from a retrospective chart review, seven patients (5 women and 2 men) aged 33−89 years were described, who developed floaters in eyes secondary to retention of dimeticone [silicone oil] droplets in eyes following administration of bevacizumab injection during treatment of wet macular degeneration, macular oedema or diabetic macular oedema. Dimeticone was administered as a lubricant along with bevacizumab [dosages and durations of therapies not stated; not all outcomes stated].
Case 1: An 89-year-old woman, who had wet macular degeneration, presented with iridescent mobile floaters. Prior to presentation, she had been receiving treatment with intravitreal bevacizumab injection, administered along with dimeticone as a lubricant. Seven weeks prior to presentation, she had received her last bevacizumab injection. She started experiencing floaters 7 days after the last bevacizumab injection. On the day of the last injection, investigations had revealed visual...
- Yu JH, et al. Silicone oil droplets following intravitreal bevacizumab injections. American Journal of Ophthalmology Case Reports 10: 142-144, Jun 2018 - USAGoogle Scholar