Reactions Weekly

, Volume 1734, Issue 1, pp 174–174 | Cite as

Desflurane/rocuronium bromide/suxamethonium chloride

Malignant hyperthermia: case report
Case report
Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A 52-year-old man developed malignant hyperthermia following the administration of desflurane, rocuronium bromide [rocuronium] and suxamethonium chloride [succinylcholine].

The man presented to a hospital with a minimally displaced right parasymphyseal fracture and moderately displaced left body fracture of the mandible. The open reduction-internal fixation of bilateral mandibular fractures was planned two days after admission. At 3:52PM, he arrived in the operating room and received induction IV rocuronium bromide 5mg as a muscle relaxant and IV suxamethonium chloride 120mg [therapeutic indication not stated] along with various other medications including unspecified antibiotics. At around 4:00PM, he started receiving desflurane gas (flow rate 6%) for maintenance of general...


  1. Gibbs IC, et al. Malignant Hyperthermia: A Case Report in a Trauma Patient. Journal of Oral and Maxillofacial Surgery 77: 54-58, No. 1, 19 Jul 2019. Available from: URL: - USA

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© Springer Nature Switzerland AG 2019

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