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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 70-year-old man developed recurrent hypotony and choroidal effusion during treatment with brimonidine and dorzolamide/timolol.
The man who had advanced pseudoexfoliation glaucoma in both eyes underwent trabeculectomy. His surgical history included argon laser trabeculoplasty in both eyes, failed trabeculectomy in the right eye followed by Ahmed valve in the right eye. Other ocular history included recurrent, acute bilateral anterior uveitis, anterior vitrectomy with sulcus intraocular lens placement in the right eye, uncomplicated cataract extraction with posterior chamber intraocular lens placement in the left eye and complex cataract extraction. Historically, his intraocular pressure (IOP) in the right eye was efficiently controlled without drops after trabeculectomy....