Reactions Weekly

, Volume 1731, Issue 1, pp 122–122 | Cite as


Tardive oromandibular dystonia: 2 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a case series, two women were described, who developed tardive oromandibular dystonia following treatment with flupentixol or pimozide as antipsychotic therapy [exact ages at the time of reaction onsets, routes, dosages and duration of treatments to reaction onsets not stated].

Patient A: An elderly woman, born in 1945, developed tardive oromandibular dystonia following treatment with flupentixol as antipsychotic therapy. In 2016, the woman presented with complaints of constant munching and biting at the age of 72 years. Her medical history included thrombocytosis and signs of Parkinson's disease . She was hospitalised at current presentation. She was found to be socially handicapped and was extremely bothered by reduced eye blinking, oromandibular, mainly biting movements,...


  1. Bakke M, et al. Interdisciplinary recognizing and managing of drug-induced tardive oromandibular dystonia: two case reports. Clinical Case Reports 6: 2150-2155, No. 11, Nov 2018. Available from: URL: - Denmark

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© Springer Nature Switzerland AG 2018

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