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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
A 62-year-old woman developed bradycardia during vasopressor therapy with norepinephrine, reversible cerebral vasoconstriction syndrome (RCVS) during treatment with escitalopram for depression, and severe headache during vasopressor therapy with phenylephrine [dosages and routes not stated; not all durations of treatments to reactions onsets stated].
The woman, who had coronary heart disease, ischaemic stroke with residual visual field deficits, hypertension, depression, hepatitis-C and seizures, was admitted with symptoms of community-acquired pneumonia. During the hospital, she started receiving escitalopram for depression and later was discharged. By day 7 after discharge, she developed acute onset right-sided weakness and presented three hours after the onset of new...
- Al-Mufti F, et al. Chemical angioplasty for medically refractory reversible cerebral vasoconstriction syndrome*. British Journal of Neurosurgery 32: 431-435, No. 4, 2018. Available from: URL: http://doi.org/10.1080/02688697.2018.1479512 - USA