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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a case series, 4 women were described aged from 50−67 years, who developed postoperative pupillary dilation and acute primary angle closure (PAC) following administration of bupivacaine/lidocaine/epinephrine [lidocaine/marcaine/adrenaline] or epinephrine [adrenaline] for local anaesthesia [routes not stated].
Case 1: A 67-year-old woman developed PAC following administration of bupivacaine/lidocaine/epinephrine. The woman underwent an upper and lower blepharoplasty in April 2006. At the time of the procedure, she received local anaesthesia (6ml at each side) with bupivacaine/lidocaine/epinephrine 0.75%/ 2%/ 1/105. She was discharged with a cold compress and eye drops containing steroid and antibiotic. Her visual acuity (VA) was 20/20 in both phakic eyes. However, 1 day after...
- Kashkouli MB, et al. Acute primary angle closure after periorbital facial procedures report of four cases and literature review. Orbit 37: 348-351, No. 5, 3 Sep 2018. Available from: URL: http://doi.org/10.1080/01676830.2017.1423352 - Iran