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Reactions Weekly

, Volume 1723, Issue 1, pp 236–236 | Cite as

Perfluorocarbon

Blindness and retinal toxicity: 7 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a retrospective analysis involving 80 patients, 7 patients aged between 47−71 years (5 men and 2 women) were described, who developed blindness related to retinal toxicity following exposure to perfluorocarbon liquid [Ala Octa] during vitreoretinal surgery [route, dosage, time to reaction onset and outcomes not stated].

Case 1: A 60-year-old man was diagnosed with superior macula-on rhegmatogenous retinal detachment on his left eye. His best corrected visual acuity (BCVA) was 20/20. Two days later, a 23G-pars plana vitrectomy with sulfur hexafluoride injection was performed. The perfluorocarbon liquid (batch number: 150414) was used along the surgery for 10 minutes. After 10 days, he developed signs of retinal toxicity such as sticking papillary traction, epiretinal fibrosis...

Reference

  1. Mendez-Martinez S, et al. BLINDNESS RELATED TO PRESUMED RETINAL TOXICITY AFTER USING PERFLUOROCARBON LIQUID DURING VITREORETINAL SURGERY. Retina 38: 1856-1864, No. 9, Sep 2018. Available from: URL: http://doi.org/10.1097/IAE.0000000000001783 - Spain

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© Springer Nature Switzerland AG 2018

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