An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a case series of three patients, two women [aged 61-74-years] were described, who developed transient corneal epithelial bullae, ocular surface toxicity or limbal stem cell deficiency following treatment with mitomycin [mitomycin-C] or latanoprost [time to reaction onset not stated; not all the dosages, routes and outcomes stated].1
Case 2: A 74-year-old woman developed corneal epithelial bullae during treatment with latanoprost for glaucoma. The woman presented with a complaint of blurry vision in the left eye. She was on ophthalmic medications, including artificial tears three times a day in both the eyes (OU). Her ocular history was significant for retinal detachment secondary to a fall. She was referred for a contact lens fitting in her left eye. She returned 6 months...