An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a retrospective study of 1287 patients, six patients (3 women and 3 men) aged 48−76 years were described, who developed symptomatic peri-procedural intracranial haemorrhage during treatment with aspirin and clopidogrel [durations of treatments to reactions onsets not stated; not all routes and outcomes stated].
Case 1: A 70-year-old woman was diagnosed with right thalamus infarction. Two years ago, she was diagnosed with an un-ruptured intracranial aneurysm. Subsequently, she started receiving dual-antiplatelet therapy with clopidogrel 75mg and aspirin 300mg daily. Thereafter, she successfully underwent stent assisted coil embolisation. However, 16 hours after procedure, she suddenly developed mental change and left-side weakness. A CT scan showed 25mm massive single right...