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An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
An 83-year-old woman developed airway obstruction following administration of alfentanil, articaine/epinephrine, mepivacaine, midazolam and propofol. Additionally, she developed transient hypertension, hypotension and bradycardia following administration of dexmedetomidine [time to reaction onset not stated; not all routes stated].
The woman presented for restorative dental treatment. She had a significant medical history of cardiovascular disease, angina, coronary artery disease, atrial fibrillation, myocardial infarction, heart murmur, mitral valve prolapse with regurgitation, aspiration pneumonia, epilepsy, hemiplegia, cerebrovascular accident, polycystic kidney disease and depression. In view of her age and the cardiovascular health history, anaesthetic management was...