Reactions Weekly

, Volume 1695, Issue 1, pp 321–321 | Cite as


Bone pain and local skin reaction related to injection: case report
Case report
Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a study, a patient [age and sex not stated] developed bone pain and local skin reaction following injection of rituximab [indication, time to reaction onset and outcome not stated]. The patient received SC rituximab 1400mg following which the patient developed bone pain and local skin reaction. The patient was consequently hospitalised.

Author comment: "One patient went back to in-hospital administration because of bone pain and local skin reaction related to injection."


  1. Wolfromm A, et al. Home administration of subcutaneous rituximab is safe and associated with significant cost saving: A single center experience. Blood 130 (Suppl. 1): 4676, Dec 2017. Available from: URL: [abstract] - France

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Personalised recommendations