Drugs & Therapy Perspectives

, Volume 35, Issue 9, pp 418–423 | Cite as

Examine the skin and thoroughly review medical/medication history when considering a diagnosis of drug-induced pigmentation

  • Adis Medical WritersEmail author
Drug Reactions and Interactions


Several medications have been implicated in drug-induced pigmentation, with evidence for the association primarily derived from case reports. The incidence rates of drug-induced pigmentation are difficult to assess and diagnosis is often complicated by the delayed onset of pigmentation and co-existing polypharmacy. Therefore, a thorough medical history, a review of current and previous medications and a complete skin examination are necessary, with subsequent discontinuation of the suspected causative agent to resolve symptoms.


Compliance with ethical standards


The preparation of this review was not supported by any external funding.

Conflict of interest

The article was adapted from the American Journal of Clinical Dermatology 2019; 20(1):75–96 [1] by employees of Adis International Ltd./Springer Nature, who are responsible for the article content and declare no conflicts of interest.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Springer NatureAucklandNew Zealand

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