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Drugs & Therapy Perspectives

, Volume 34, Issue 11, pp 517–517 | Cite as

First reports of adverse drug reactions

Drug Reactions and Interactions
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Table 1 contains an overview of first published case reports of adverse drug reactions identified in the international literature in recent weeks by Reactions Weekly, the Adis drug safety newsletter. Reactions Weekly provides summaries of adverse drug reaction news sourced from journals, scientific meetings, media releases, regulatory agency websites, and bulletins from the National Centers that participate in the WHO International Drug Monitoring Programme.
Table 1

First published reports of adverse drug reactions recently identified by Reactions Weekly

Drug and adverse reaction

References

Clopidogrel: small bowel ulcer (serious)

Ebi M, Inoue S, Sugiyama T, et al. A small bowel ulcer due to clopidogrel with cytomegalovirus enteritis diagnosed by capsule and double-balloon endoscopy. Case Rep Gastroenterol 2018;12(2):303–10.  https://doi.org/10.1159/000490096

Cyclizine: Nicolau syndrome (serious)

Tabor D, Bertram CG, Williams AJK, et al. Nicolau syndrome (embolia cutis medicamentosa): a rare and poorly recognized iatrogenic cause of cutaneous thrombotic vasculopathy. Am J Dermatopathol. 2018;40(3):212–5.  https://doi.org/10.1097/dad.0000000000000972

Ibrutinib: Sweet syndrome (serious)

El Halabi L, Cherif-Rebai K, Michot JM, et al. Ibrutinib-induced neutrophilic dermatosis. Am J Dermatopathol. 2018;40(3):198–200.  https://doi.org/10.1097/dad.0000000000000862

Triptorelin: transient hyperthyroidism (serious)

Miao J, Yan Q, Wang L, et al. Three cases of transient hyperthyroidism after triptorelin treatment-case report and literature review. Gynecol Endocrinol. 2018;34(9):734–5.  https://doi.org/10.1080/09513590.2018.1445710

An event is serious (US FDA MedWatch definition) when the patient outcome is death, life threatening, hospitalization, disability, congenital anomaly or requires intervention to prevent permanent impairment or damage

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