Drugs & Therapy Perspectives

, Volume 35, Issue 1, pp 21–23 | Cite as

Pre-exposure prophylaxis for HIV infection may be effective in older candidates, but proceed with caution

  • Adis Medical WritersEmail author
Disease Management


The effectiveness and safety of tenofovir (TDF)-based therapy, which is the standard for pre-exposure prophylaxis (PrEP) for HIV infection, have not been specifically evaluated in older individuals. Major concerns relate to the older population being predisposed to kidney- and/or bone-related adverse events if they receive TDF-based PrEP. However, TDF-based PrEP may be a manageable treatment option in older candidates if careful screening, regular monitoring and appropriate sexual health education are also incorporated into the prevention plan.


Compliance with ethical standards

Conflict of interest

The article was adapted from Drugs & Aging 2018;35(6):485–91 [4] by employees of Adis/Springer, who are responsible for the article content and declare no conflicts of interest.


The preparation of this review was not supported by any external funding.


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© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.SpringerAucklandNew Zealand

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