Overcome the challenges of drug administration in children by developing age-appropriate formulations
- 29 Downloads
Interest in developing age-appropriate formulations of drugs to optimize pharmacological therapy in children continues to grow. With oral formulations being the most common route of administration, several factors relating to the formulation and bitter taste of drugs can impact the acceptability of medications in children. Approaches to improve medication acceptability include the use of alternative delivery systems, taste-masking strategies and the development of new technologies for formulation preparation.
Compliance with ethical standards
Conflict of interest
The article was adapted from Pharmaceutical Medicine 2018;32(1):21-30  by employees of Adis/Springer, who are responsible for the article content and declare no conflicts of interest.
The preparation of this review was not supported by any external funding.
- 1.Rieder M. Size and taste matters: recent progress in the development of age-appropriate medicines for children. Pharmaceut Med. 2018;32(1):21–30.Google Scholar
- 4.Zajicek A, Fossler MJ, Barrett JS, et al. A report from the pediatric formulations task force: perspectives on the state of child-friendly oral dosage forms. AAPS Pharm Sci Tech. 2013;15:1072–81.Google Scholar
- 25.Guideline on pharmaceutical development of medicines for paediatric use. London: European Medicines Agency; 2013.Google Scholar