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Highly Active Pd-PEPPSI Complexes for Suzuki-Miyaura Cross-coupling of Aryl Chlorides: an Investigation on the Effect of Electronic Properties

  • Yingying Zhang
  • Fangwai Han
  • Mengyao Zhang
  • Huixin Zhang
  • Ying Li
  • Ru Wang
  • Yongfei ZengEmail author
  • Guiyan LiuEmail author
Article
  • 2 Downloads

Abstract

Three new Pd-pyridine enhanced precatalyst preparation stabilization and initiation(PEPPSI) complexes with halogen groups on the N-heterocyclic carbene and pyridine were prepared. Their structures have been clearly characterized by nuclear magnetic resonance spectroscopy and X-ray single-crystal diffraction. The effects of the electronic properties of halogen groups on the catalytic activity in the Suzuki-Miyaura cross-coupling of aryl chlorides were investigated. These Pd-PEPPSI complexes could catalyze the cross-coupling reaction efficiently with a low catalyst loading(0.05%, molar ratio) at room temperature and the products were obtained in high yields.

Keywords

Pd-pyridine enhanced precatalyst preparation stabilization and initiation(PEPPSI) complex; Suzu-ki-Miyaura cross-coupling reaction Aryl chloride 

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Highly Active Pd-PEPPSI Complexes for Suzuki-Miyaura Cross-coupling of Aryl Chlorides: an Investigation on the Effect of Electronic Properties

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Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH 2019

Authors and Affiliations

  • Yingying Zhang
    • 1
  • Fangwai Han
    • 1
  • Mengyao Zhang
    • 1
  • Huixin Zhang
    • 1
  • Ying Li
    • 1
  • Ru Wang
    • 1
  • Yongfei Zeng
    • 1
    Email author
  • Guiyan Liu
    • 1
    Email author
  1. 1.Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-organic Hybrid Functional Material Chemistry, Ministry of Education, College of ChemistryTianjin Normal UniversityTianjinP. R. China

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