Chemical Research in Chinese Universities

, Volume 35, Issue 4, pp 556–559 | Cite as

Synthesis and Characterization of 3-Phenyl-adamantane-1-carboxylic Acid

  • Wei Feng
  • Kaiqi Ye
  • Yang JiangEmail author
  • Ruibin Hou


Adamantane and its derivatives have been introduced into many drugs for current clinical research and some of them are used for the treatment of neurological disease and/or used as the antiviral agents as well as the agents against type-2 diabetes. Recently, there have been many relevant research reported for developing medicinal chemistry by employing the adamantyl group. In this paper, a new adamantane-based compound (3-phenyl-adamantane-1-carboxylic acid, PACA) was synthesized and characterized by X-ray diffraction(XRD), thermogravimeric analysis(TGA), Fourier transform infrared spectroscopy(FTIR), etc., which should be a beneficial complement or extension to the existing adamantyl-based materials.


Adamantane Cage-like molecule Medicinal chemistry Single crystal 


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Supplementary material

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Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH 2019

Authors and Affiliations

  1. 1.China-Japan Union Hospital of Jilin UniversityChangchunP. R. China
  2. 2.State Key Laboratory of Supramolecular Structure and Materials, College of ChemistryJilin UniversityChangchunP. R. China
  3. 3.Advanced Institute of Materials Science, College of Chemistry and Life ScienceChangchun University of TechnologyChangchunP. R. China

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