Tandem Approach to Functionalized Pyrrolo[3,4-a]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation
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A one-pot and efficient three-component reaction of indoles, acrylates and maleimides for the synthesis of pyrrolo[3,4-a]carbazole-1,3-dione derivatives was developed. Theree C-C bonds and one ring were created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C3-alkenylation of indoles.
KeywordsCarbazole One-pot Tandem reaction Three-component reaction Indole-to-carbazole
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- Biswas S., Dagar A., Srivastava A., Samanta S., Eur. J. Org. Chem., 2015, 4493Google Scholar