Chemical Research in Chinese Universities

, Volume 35, Issue 4, pp 621–626 | Cite as

Tandem Approach to Functionalized Pyrrolo[3,4-a]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation

  • Lianghua Guo
  • Mei Xu
  • Yong Jian
  • Sheng Liu
  • Weidong PanEmail author
  • Lian DuanEmail author


A one-pot and efficient three-component reaction of indoles, acrylates and maleimides for the synthesis of pyrrolo[3,4-a]carbazole-1,3-dione derivatives was developed. Theree C-C bonds and one ring were created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C3-alkenylation of indoles.


Carbazole One-pot Tandem reaction Three-component reaction Indole-to-carbazole 


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Supplementary material

40242_2019_8399_MOESM1_ESM.pdf (951 kb)
A Tandem Approach to Functionalized Pyrrolo[3,4-a]carbazole-1,3-diones via an Pd-catalyzed Indole-to-carbazole Transformation


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Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH 2019

Authors and Affiliations

  1. 1.State Key Laboratory of Functions and Applications of Medicinal PlantsGuizhou Medical UniversityGuiyangP. R. China

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