Neuroplasticity in Brain Injury: Maximizing Recovery

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Purpose of Review

The ability to promote greater neuroplasticity through external influencers is an emerging field of study with potentially significant consequences on the treatment of neurologic injury. Several of these methods are reviewed in this paper.

Recent Findings

Through advances in neuroscience, a clearer understanding of the complexity of the brain’s interconnectedness and its ability to adapt to the environment is leading to neurorehabilitation treatments that augment the brain’s capacity towards neuroplastic change.


An increased appreciation and recognition of neuroplasticity has led to novel approaches to promote neurorecovery that increase stimulation and the release of neutrophic factors. Some of these interventions include the use of pharmacologic agents, noninvasive stimulation, mirror therapy, aerobic and task-specific exercise, and the maximization of sleep. Future research will continue to build upon this foundation by continuing to pair therapeutic interventions with rehabilitation to enhance the brain’s natural healing power and improve functional outcomes.

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    Correspondence to Neil Jasey.

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    Neil Jasey and Irene Ward declare that they have no conflicts of interest.

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    This article is part of the Topical Collection on Brain Injury Medicine and Rehabilitation

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    Jasey, N., Ward, I. Neuroplasticity in Brain Injury: Maximizing Recovery. Curr Phys Med Rehabil Rep 7, 333–340 (2019).

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    • Neuroplasticity
    • Neural plasticity
    • Neurorecovery
    • Rehabilitation
    • Brain injury