Current Radiology Reports

, 6:29 | Cite as

PET/CT and Bone Scintigraphy: Metabolic Results in Musculoskeletal Lesions

  • Rosj Gallicchio
  • Anna Nardelli
  • Piernicola Pedicini
  • Giuseppe Guglielmi
  • Giovanni StortoEmail author
Geriatrics (G Guglielmi, Section Editor)
Part of the following topical collections:
  1. Geriatrics



This review aimed to provide an overview on findings from metabolic imaging modalities such as bone scintigraphy and positron emission tomography–computed tomography (PET/CT) in musculoskeletal lesions. It is conceivable that methods assessing metabolism of bone tumors, combined with the morphological assessment, could enhance the possibility for a personalized therapy with particular emphasis to malignant neoplasms.

Recent Findings

The assessment of bone tumors by conventional scintigaphic and morphological imaging has been recently integrated with the morpho-metabolic appraisal obtained by PET/CT systems. Increasing availability of this diagnostic modality has been shown to stratify properly the patients and the findings correlate well with outcome. Moreover, new tracers are being implemented in the study of musculoskeletal lesions by PET/CT while the new volumetric parameters used to identify the lesions hold great promise.


Results from PET/CT are associated with tumor grading and histopathology in bone malignant lesions and they could be of value for implementing treatment strategy. Additionally, the metabolic assessment has been demonstrated useful for predicting surgical response and patients’ outcome.


PET/CT Bone scintigraphy Musculoskeletal neoplasms Metabolic findings Diagnosis and follow-up 


Compliance with Ethical Guidelines

Conflict of interest

Rosj Gallicchio, Anna Nardelli, Piernicola Pedicini, and Giovanni Storto each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Recently published papers of particular interest have been highlighted as: • Of importance •• Of major importance

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Rosj Gallicchio
    • 1
  • Anna Nardelli
    • 2
  • Piernicola Pedicini
    • 1
  • Giuseppe Guglielmi
    • 3
  • Giovanni Storto
    • 1
    Email author
  1. 1.Medicina Nucleare, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)Centro di Riferimento Oncologico della Basilicata (CROB)Rionero in VultureItaly
  2. 2.Istituto di Biostrutture e BioimmaginiConsiglio Nazionale delle Ricerche (CNR)NaplesItaly
  3. 3.Dipartimento di RadiologiaUniversità di FoggiaFoggiaItaly

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