A Comprehensive Review on the Nutritional and Nutraceutical Aspects of Garden Cress (Lepidium sativum Linn.)

  • Tanu Jain
  • Kiran Grover


Studies revealed that garden cress (Lepidium sativum) has been used in India for medicinal purposes since Vedic era. A systematic literature review was conducted to summarize and quantify the past and current evidence for garden cress. Relevant papers up to 2015 in various databases were searched to collect the review on garden cress. Garden cress, a native of Egypt and south west Asia, is a small perennial edible herb that has been used to treat many diseases for centuries. The seeds, leaves as well as roots have medicinal properties. The seeds are rich in protein, fat, calcium, iron and have high nutritional value. They are considered to be galactogogue, anticarcinogenic, antidiabetic, antiasthmatic and antidiarrheal. The article also emphasized on the nutritional composition of the leaves which showed that these are good source of macroelements like potassium, sodium, calcium and trace minerals like iron, magnesium and zinc. The food products developed by using garden cress seed powder have also been highlighted in the present review.


Anticarcinogenic Antidiabetic Galactogogue Laxative Nutritional value 



One of the authors expresses her gratitude to the University Grant Commission (UGC), New Delhi, India for the award of the Junior Research Fellowship.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

40011_2016_775_MOESM1_ESM.docx (11 kb)
Supplementary material 1 (DOCX 12 kb)
40011_2016_775_MOESM2_ESM.docx (11 kb)
Supplementary material 2 (DOCX 12 kb)


  1. 1.
    Tiwari PN, Kulmi GS (2004) Performance of Chandrasur (Lepidium sativum) under different levels of nitrogen and phosphorus. J Med Aromat Plant Sci 26:479–481Google Scholar
  2. 2.
    Divanji M, Viswanatha GL, Nagesh S, Jain V, Shivaprasad HN (2012) Ethnopharmacology of Lepidium Sativum Linn. (Brassicaceae): a review. Int J Phytother Res 2:1–7Google Scholar
  3. 3.
    Roy B, Wivay J, Remco W, Xander W (2002) Altering the taste of plants and vegetable. J Lipids 12:951–956Google Scholar
  4. 4.
    Gokavi SS, Malleshi NG, Guo M (2004) Chemical composition of garden cress (Lepidium sativum) seeds and its fractions and use of bran as a functional ingredient. Plant Foods Hum Nutr 59:105–111CrossRefPubMedGoogle Scholar
  5. 5.
    Sood SK, Kaushal S, Lakhanpal TN, Kumar S (2011) Ethnic healing herbs for cold, flu and lungs ailments. Daya publishing House, Delhi, p 113Google Scholar
  6. 6.
    Patel U, Kulkarni M, Undale V, Bhosale A (2009) Evaluation of diuretic activity of aqueous and methanol extracts of Lepidium sativum garden cress (Cruciferae) in rats. Trop J Pharm Res 8:215–219CrossRefGoogle Scholar
  7. 7.
    Doke S, Guha M (2014) Garden cress (Lepidium sativum L.) seed-an important medicinal source: a review. J Nat Prod Plant Resour 4:69–80Google Scholar
  8. 8.
    Gopalan C, Sastri BVR, Balasubramanian SC, Narsinga Rao BS, Deosthale YG, Pant KC (2011) Nutritive value of indian foods. National Institute of Nutrition, Indian Council of Medical Research (ICMR), HyderabadGoogle Scholar
  9. 9.
    Hernandez BJE, Leon J (1994) Neglected crops: 1492 from a different perspective FAO plant production and protection. Food And Agriculture Organization of United Nations, Rome, pp 307–310Google Scholar
  10. 10.
    Dhiman AK (2006) Ayuvedic drug plant. Daya Publishing House, Delhi, p 98Google Scholar
  11. 11.
    Ensminger ME, Ensminger AH (1993) Food and nutrition encyclopedia. CRC Press, USA, p 514Google Scholar
  12. 12.
    Nadkarni AK (1954) Nora Indian material medical. Popular Prakashan Private Limited, Bombay, pp 736–737Google Scholar
  13. 13.
    Prajapati ND, Purohit SS, Sharma AK, Kumar T (2003) A handbook of medicinal plant, a complete source book. Agrobios (India), Agrohouse, Jodhpur, pp 312–313Google Scholar
  14. 14.
    Bigoniya P, Singh CS, Shukla A (2011) Pharmacognostical and physicochemical standardization of ethnopharmacologically important seeds of Lepidium sativum Linn. and Wrightia tinctoria R Br. Indian J Nat Prod Resour 2:464–471Google Scholar
  15. 15.
    Prajapati VD, Maheriya PM, Jani GK, Patil PD, Patel BN (2014) Lepidium sativum Linn.: a current addition to the family of mucilage and its applications. Int J Biol Macromol 65:72–80CrossRefPubMedGoogle Scholar
  16. 16.
    Karazhiyan H, Razavi SMA, Phillips GO (2011) Extraction optimization of a hydrocolloid extract from cress seed (Lepidium sativum) using response surface methodology. Food Hydrocoll 25:915–920CrossRefGoogle Scholar
  17. 17.
    Razavi SMA, Farhoosh R, Bostan A (2007) Functional properties of hydrocolloid extract of some domestic Iranian seeds. Research project No. 1475, Unpublished report, Ferdowsi University of Mashhad, IranGoogle Scholar
  18. 18.
    Al- Jassas FM, Al- Jasser MS (2012) Chemical composition and fatty acid content of some spices and herbs under Saudi Arebia conditions. Sci World J. doi: 10.1100/2012/859892 CrossRefGoogle Scholar
  19. 19.
    Gaafar AM, Morsi AA, Elghamry HE (2013) Chemical, nutritional and biochemical studies of garden cress protein isolate. Nat Sci 11:8–13Google Scholar
  20. 20.
    Mohammed Ali RF (2013) Preparation and characterization of protein isolate and biodiesel from garden cress seed. Eur J Chem 4(2):85–91CrossRefGoogle Scholar
  21. 21.
    Zia-Ul-Haq M, Ahmad S, Calani L, Mazzeo T, Rio DD, Pellegrini N, De Feo V (2012) Compositional study and antioxidant potential of Ipomoea hederacea Jacq. and Lepidium sativum L. seeds. Molecules 17:10306–10321CrossRefPubMedGoogle Scholar
  22. 22.
    Diwakar BT, Dutta PK, Belur RL, Kamatham Naidu KA (2010) Physicochemical properties of garden cress (Lepidium sativum L.) seed oil. J Am Oil Chem Soc 87:539–548CrossRefGoogle Scholar
  23. 23.
    Moser BR, Shah SH, Winkler-Moser JK, Vaughn SF, Evangelista RL (2009) Composition and physical properties of cress (Lepidium sativum L.) and field pennycress (Thlaspi arvense L.) oils. Ind Crops Prod 30:199–205CrossRefGoogle Scholar
  24. 24.
    Hassan LG, Hassan SW, Hashim T, Umar KJ, Sani Bayero NA (2011) Determination of nutritive values of garden cress (Lepidium sativum L.) leaves. J Pure Appl Sci 4:18–23Google Scholar
  25. 25.
    Kirtikar KR, Basu BD (2004) Indian medicinal plants. Bishen Singh Mahendra Pal Singh, Dehradun, p 174Google Scholar
  26. 26.
    Rastogi RP, Mehrotra, BN (1990) Compendium of Indian Medicinal Plants. CDRI, Lucknow; Publication and information Directorate, New Delhi, pp 1960–1969Google Scholar
  27. 27.
    Maier UH, Gundlach H, Zenk MH (1998) Seven imidazole alkaloids from Lepidium sativum. Phytochem 49:1791–1795CrossRefGoogle Scholar
  28. 28.
    Nayak PS, Upadhyaya SD, Upadhyaya A (2009) A HPTLC densitometer determination of sinapic acid in chandrasur (Lepidium sativum). J Sci Res 1:121–127Google Scholar
  29. 29.
    Sharma RK, Vyas K, Manda H (2012) Evaluation of antifungal effect on ethanolic extract of Lepidium sativum L. seed. Int J Phytopharmacol 3:117–120Google Scholar
  30. 30.
    Yadav YC, Srivastav DN, Saini V, Seth AK, Ghelani TK, Malik A, Kumar S (2011) In-vitro antioxidant activities of ethanolic extract of Lepidium sativum L. seeds. Int J Pharm Sci 2:244–253Google Scholar
  31. 31.
    Radwan HM, El-Missiry MM, Al-Said WM, Ismail AS, Abdel SKA, Saif- El-Nasr MM (2007) Investigation of the glucosinolates of Lepidium sativum growing in Egypt and their biological activity. Res J Med Med Sci 2:127–132Google Scholar
  32. 32.
    Rehman N, Mehmood MH, Alkharfy KM, Gilani AH (2011) Prokinetic and laxative activities of Lepidium sativum seed extract with species and tissue selective gut stimulatory actions. J Ethnopharmacol 134:878–883CrossRefGoogle Scholar
  33. 33.
    Sood SK, Parmar S, Lakhanpal TN (2005) Ethnic PLANTS of India, used in cancer cure—a compendium. Bishen Singh Mahendra Pal Singh, Dehradun, p 172Google Scholar
  34. 34.
    Chopra RN, Nayar SL, Chopra IC (2006) Glossary of Indian medicinal plants. National Institute of Science Communication and Information resources (CSIR), New Delhi, pp 845–846Google Scholar
  35. 35.
    Chopra RN, Badhwar RL, Ghosh S (1965) Poisonous plants of India. Indian Council of Agricultural Research (ICAR), New Delhi, p 972Google Scholar
  36. 36.
    Mahassni SH, Al-Reemi RM (2013) Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds. Saudi J Biol Sci 20:131–139CrossRefPubMedPubMedCentralGoogle Scholar
  37. 37.
    Tiwari BK, Brunton NP, Brennan CS (2012) Handbook of plant food phytochemicals, sources, stability and extraction. Wiley Blackwell, UK, p 105Google Scholar
  38. 38.
    Maghrani M, Zeggwah N, Michel J, Eddouks M (2005) Antihypertensive effect of Lepidium sativum in spontaeneously hypertensive rats. J Ethnophamacol 100:193–197CrossRefGoogle Scholar
  39. 39.
    Eddouks M (2004) Nutritional, elemental analysis and antioxidant activity of garden cress seeds. Int J Pharm Sci 4:390–395Google Scholar
  40. 40.
    Patole AP, Agie VV, Phadnis MC (1998) Effect of mucilaginous seeds on in vitro rate of starch hydrolysis and blood glucose levels of NIDDM subjects with special reference to garden cress seeds. J Med Aromat Plant Sci 20:1005–1008Google Scholar
  41. 41.
    Diwakar BT, Dutta PK, Lokesh BR, Naidu KA (2008) Bioavailability and metabolism of n-3 fatty acid rich garden cress (Lepidium sativum) seed oil in albinorats. Prostaglandins Leukot Essent Fatty Acids 78:123–130CrossRefPubMedGoogle Scholar
  42. 42.
    Drevon CA (1992) Marine oils and their effects. Nutr Rev 50:38–45CrossRefPubMedGoogle Scholar
  43. 43.
    Simopoulos AP (1991) ω-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr 54:438–463CrossRefPubMedGoogle Scholar
  44. 44.
    Paranjape AN, Mehta AA (2006) A study on clinical efficacy of Lepidium sativum seeds in treatment of bronchial asthma. Iran J Pharmacol Ther 5:55–59Google Scholar
  45. 45.
    Juma ABHA (2007) The effect of Lepidium sativum seeds on fracture induced healing in rabbits. Medscape Gen Med 9:23Google Scholar
  46. 46.
    Bhasin P, Bansal D, Yadav OP, Punia A (2011) In vitro antioxidant activity and phytochemical analysis of seed extracts of Lepidium sativum—a medicinal herb. J Biosci Tech 2:410–415Google Scholar
  47. 47.
    Indumathy R, Aruna A (2013) Free radical scavenging activities, total phenolic and flavonoid content of Lepidium sativum (Linn.). Int J Pharm Pharm Sci 5:634–637Google Scholar
  48. 48.
    Adam SE (1999) Effects of various levels of dietary Lepidium sativum L. seeds in rats. Am J Chin Med 27:397–405CrossRefPubMedGoogle Scholar
  49. 49.
    Bafeel SO, Ali SS (2009) The potential liver toxicity of Lepidium sativum seeds in albino rats. Res Biol Sci 4:1250–1258Google Scholar
  50. 50.
    Datta PK, Diwaker BT, Viswanatha S, Murthy KN, Naidu KA (2011) Safety evaluation studies on Garden cress (Lepidium sativum L.) seeds in Wistar rats. Int J Appl Res Nat Prod 4:37–43Google Scholar
  51. 51.
    Zanvar VS, Devi R (2007) Biofortification of biscuits with garden cress for prevention of anemia. Asian J Home Sci 2:1–15Google Scholar
  52. 52.
    Mohite SY, Ghara DBL, Ranveer RC, Sahoo AK, Ghosh JS (2012) Development of health drink enriched with processed garden cress (Lepidium sativum L.) seeds. Am J Food Technol 7:571–576CrossRefGoogle Scholar
  53. 53.
    Agarwal N, Sharma S (2013) Appraisal of garden cress (Lepidium sativum L.) and product development as an all pervasive and nutrition worthy food stuff annals. Ann Food Sci Technol 14:77–84Google Scholar
  54. 54.
    Kotagi K, Chimmad B, Naik R, Kamatar MY (2013) Nutrient enrichment of little millet (Panicum miliare) flakes with garden cress seeds. Int J Food Sci Nutr 2:36–39Google Scholar
  55. 55.
    Guddad S, Bharati P (2014) Formulation and evaluation of cereal based health mix for pre-school children. Asian J Home Sci 9:44–49Google Scholar
  56. 56.
    Sharma S, Agarwal N, Choudhary RA (2013) Bengal gram dhal flour ladoo improvisation incorporating red kidney beans (Phaseolus vulgaris L.) and garden cress seeds (Lepidium sativum L.). J Sci Technol 2(1):71–79Google Scholar
  57. 57.
    Elizabeth KGG, Poojara RH (2014) Organoleptic attributes of garden cress seed incorporated snacks suitable for adolescents. Int J Food Nutr Sci 3(6):126–129Google Scholar
  58. 58.
    Angel M, Devi KPV (2015) Therapeutic impact of garden cress seeds incorporated ladoo among the selected anaemic adolescent girls (12–15 years). J Drug Discov Ther 3:18–22Google Scholar
  59. 59.
    Lohekar AS, Arya AB (2014) Development of value added instant ‘dhokla’ mix. Int J Food Nutr Sci 3:78–83Google Scholar
  60. 60.
    Nathiya M, Vigasini N (2014) Formulation of cereal based nutricookies prepared incorporating garden cress seeds (Lepidium sativum)—a protein and iron rich snack. Int J Sci Res 3:225–226Google Scholar
  61. 61.
    Agarwal N, Sharma S (2011) Garden cress: an untapped environmentally sustainable foodstuff and health enhancer. J Hum Dev 3(1):63–70Google Scholar
  62. 62.
    Angel M, Devi KPV (2014) Effect of garden cress seeds incorporated health mix among selected anaemic adolescent girls (12–15 years) in Dindigul district, Tamil Nadu, India. Int J Sci Res 3:64–66Google Scholar

Copyright information

© The National Academy of Sciences, India 2016

Authors and Affiliations

  1. 1.Department of Food and NutritionPunjab Agricultural UniversityLudhianaIndia

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