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Pneumo News

, Volume 10, Issue 7, pp 32–36 | Cite as

Pneumologie meets Gastro

Gastroösophagealer Reflux als Auslöser von Husten und Asthma

  • Adrian Gillissen
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Gastroösophagealer Reflux (GERD) und Asthma bronchiale treten häufig zusammen auf. Und da Husten in den frühen Morgenstunden für beide Erkrankungen typisch ist, lassen sie sich klinisch mitunter schwer unterscheiden. Bis zu 80 % aller Asthmapatienten haben einen GERD, allerdings nur wenige die charakteristischen Refluxzeichen. Eine GERD-Therapie macht bei Asthmapatienten ohne Refluxsymptome keinen Sinn. Hier gilt es, den richtigen Pfad einzuschlagen.

Literatur

  1. 1.
    El-Serag HB, Sweet S, Winchester CC et al (2014) Update on the epidemiology of gastrooesophagealreflux disease: a systematic review. Gut 63:871–880CrossRefGoogle Scholar
  2. 2.
    Koop H, Fuchs KH, Labenz J et al (2014) S2k-Leitlinie: Gastroösophageale Refluxkrankkheit unter Federführung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS). Z Gastroenterol 52:1299–1346CrossRefGoogle Scholar
  3. 3.
    Gillessen A, Virchow JC (2003) Gastroösophagealer Reflux und Asthma. Dtsch Med Wochenschr 128:2427–2430CrossRefGoogle Scholar
  4. 4.
    Fass R, Quan SF, O’Connor GT etal (2005) Predictors of heartburn during sleep in a large prospective cohort study. Chest 127:1658–1666CrossRefGoogle Scholar
  5. 5.
    Cazzola M, Bettoncelli G, Sessa E et al (2010) Prevalenceofcomorbidities inpatientswithchronic obstructive pulmonary disease. Respiration 80:112–119CrossRefGoogle Scholar
  6. 6.
    Havemann BD, Henderson CA, El-Serag HB (2007) The association between gastro-oesophageal reflux disease and asthma: a systematic review. Gut 56:1654–1664CrossRefGoogle Scholar
  7. 7.
    Kardos P, Berck H, Fuchs KH et al (2010) Leitlinie der Deutschen Gesellschaft für Pneumologie zur Diagnostik und Therapie von Patienten mit akutem oder chronischemHusten. Pneumologie 64:701–711CrossRefGoogle Scholar
  8. 8.
    Symptom Husten GA (2007) Kennen Sie die diagnostischen Fallstricke? MMW Fortschr Med 51–52:47–51Google Scholar
  9. 9.
    Irwin RS, Ownbey R, Cagle PT et al (2006) Interpreting the histopathology of chronic cough: a prospective, controlled, comparative study. Chest 130:362–370CrossRefGoogle Scholar
  10. 10.
    Irwin RS (2006) Chronic cough due to gastroesophageal reflux disease: ACCP evidence-based clinical practice guidelines. Chest 129:80S–94SCrossRefGoogle Scholar
  11. 11.
    Irwing RS, Boulet L-P, Cloutier MM et al (1998) Managing cough as a defense mechanism and as a symptom. A consensus panel report of the Amercian Chest Physicians. Chest 114:133S–181SCrossRefGoogle Scholar
  12. 12.
    Kahrilas PJ, Shaheen NJ, Vaezi MF et al (2008) American Gastroenterological Association medical position statement on the management of gastroesophageal reflux disease. Gastroenterology 135: 1383–1391CrossRefGoogle Scholar
  13. 13.
    Solidoro P, Patrucco F, Fagoonee S et al (2017) Asthma and gastroesophageal reflux disease: a multidisciplinary point of view. Minerva Med 108:350–356PubMedGoogle Scholar
  14. 14.
    Garcia Rodriguez LA, Ruigomez A, Martin-Merino E et al (2008) Relationship between gastroesophageal reflux disease and COPD in UK primarycare. Chest 134:1223–1230CrossRefGoogle Scholar
  15. 15.
    Ruigomez A, Rodriguez LA, Wallander MA et al (2005) Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice. Chest 128:85–93CrossRefGoogle Scholar
  16. 16.
    Ruhl CE, Sonnenberg A, Everhart JE (2001) Hospitalization with respiratory disease following hiatal hernia and reflux esophagitis in a prospective, population-based study. Ann Epidemiol 11:477–483CrossRefGoogle Scholar
  17. 17.
    Coughlan JL, Gibson PG, Henry RL (2001) Medical treatment for reflux oesophagitis does not consistently improve asthmacontrol: a systematic review. Thorax 56:198–204CrossRefGoogle Scholar
  18. 18.
    Gibson PG, Henry RL, Coughlan JL (2003) Gastrooesophageal reflux treatment for asthma in adults and children. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD001496Google Scholar
  19. 19.
    Bocskei C, Viczian M, Bocskei R et al (2005) The influence of gastroesophageal reflux disease and its treatment on asthmatic cough. Lung 183:53–62CrossRefGoogle Scholar
  20. 20.
    Hunt R, Armstrong D, Katelaris P et al (2017) World Gastroenterology Organisation global guidelines: GERD Global Perspective on Gastroesophageal Reflux Disease. J Clin Gastroenterol 51:467–478CrossRefGoogle Scholar
  21. 21.
    Bittinger M, Geißler B, Probst A et al (2014) S2k-Leitlinie. Gastroösophageale Refluxkrankheit. Bayer Azteb l10:488–495Google Scholar
  22. 22.
    Tutuian R, Clinical Lead Outpatient S, Gastrointestinal Function L (2010) Adverse effects of drugs on the esophagus. Best Pract Res Clin Gastroenterol 24:91–97CrossRefGoogle Scholar
  23. 23.
    Avidan B, Sonnenberg A, Schnell TG et al (2002) There are no reliable symptoms for erosive oesophagitis and Barrett’s oesophagus: endoscopic diagnosis is still essential. Aliment Pharmacol Ther 16:735–742CrossRefGoogle Scholar
  24. 24.
    Jaspersen D, Kulig M, Labenz J et al (2003) Prevalence of extra-oesophageal manifestations in gastro-oesophageal reflux disease: an analysis based on the ProGERD Study. Aliment Pharmacol Ther 17:1515–1520CrossRefGoogle Scholar
  25. 25.
    Jaspersen D, Labenz J, Willich S N et al (2006) Longterm clinical course of extra-oesophageal manifestations in patients with gastro-oesophageal reflux disease. A prospective follow-up analysis based on the ProGERD study. Dig Liver Dis 38:233–238CrossRefGoogle Scholar
  26. 26.
    Kulig M, Nocon M, Vieth M et al (2004) Risk factors of gastroesophageal reflux disease: methodology and first epidemiological results of the ProGERD study. J Clin Epidemiol 57:580–589CrossRefGoogle Scholar
  27. 27.
    Nakada K, Matsuhashi N, Iwakiri K et al (2017) Development and validation of a simple and multifaceted instrument, GERD-TEST, for the clinical evaluation of gastroesophageal reflux and dyspeptic symptoms. World J Gastroenterol 23:5216–5228CrossRefGoogle Scholar
  28. 28.
    Iwasaki A, Yosinaga Y, Kawahara K et al (2003) Evaluation of lung volume reduction surgery (LVRS) based on long-term survival rate analysis. Thorac Cardiovasc Surg 51:277–282CrossRefGoogle Scholar
  29. 29.
    Lacy BE, Chehade R, Crowell MD (2011) A prospective study to compare a symptombased reflux disease questionnaire to 48-h wireless pH monitoring for the identification of gastroesophageal reflux (revised 2-26-11). Am J Gastroenterol 106:1604–1611CrossRefGoogle Scholar
  30. 30.
    Lacy BE, Weiser K, Chertoff J et al (2010) The diagnosis of gastroesophageal reflux disease. Am J Med 123:583–592CrossRefGoogle Scholar
  31. 31.
    Wang WH, Huang JQ, Zheng GF et al (2005) Is proton pump inhibitor testing an effective approach to diagnose gastroesophageal reflux disease in patients with noncardiac chest pain?: ameta-analysis. Arch Intern Med 165:1222–1228CrossRefGoogle Scholar
  32. 32.
    Numans ME (2006) The use of proton pump inhibitors as a diagnostic test for gastroesophageal reflux disease. Arch Intern Med 166:247–248 (author reply248–249)CrossRefGoogle Scholar
  33. 33.
    Numans ME, Lau J, de Wit NJ etal (2004) Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics. Ann Intern Med 140:518–527CrossRefGoogle Scholar
  34. 34.
    Amarasiri LD, Pathmeswaran A, de Silva HJ et al (2010) Prevalence of gastro-oesophageal reflux disease symptoms and reflux-associated respiratory symptoms in asthma. BMC PulmMed 10:49CrossRefGoogle Scholar
  35. 35.
    Sifrim D (2013) Management of bile reflux. GastroenterolHepatol (NY) 9:179–180Google Scholar
  36. 36.
    Sifrim D, Zerbib F (2012) Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors. Gut 61:1340–1354CrossRefGoogle Scholar
  37. 37.
    Woodland P, Sifrim D (2013) Management of gastro-oesophageal reflux disease symptoms that do not respond to proton pump inhibitors. Curr Opin Gastroenterol 29:431–436CrossRefGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Medizinische Klinik III, Klinikum am Steinenberg / ErmstalklinikMed. Klinik III Innere Medizin/PneumologieReutlingen-Bad UrachDeutschland

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