Interest of immunodeficiency screening in adult after admission in medical intensive care unit for severe infection, a retrospective and a prospective study: the Intensive Care Unit and Primary and Secondary Immunodeficiency (ICUSPID) study
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Primary immunodeficiency (PID) in adults is rare and mostly revealed by infections.
Material and Methods
Adults without predisposing factors who were admitted to an intensive care unit (ICU) for infection were screened for PID.
Six PID cases were diagnosed, mostly revealed by encapsulated bacterial infections.
Investigation of PID after ICU discharge should be considered to improve early detection.
KeywordsPrimary immunodeficiency Secondary immunodeficiency Infection Adult Intensive care unit
The authors acknowledge the French National Reference Centre for PID, CEREDIH.
AB, NMS, GM, AS, AS, SD, DDC, AJ, NM and BB collected the data and drafted the report. AB, NMS, GM analyzed and interpreted the data. All authors read and approved the final report.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 4.EUROPEAN SOCIETY FOR IMMUNODEFICIENCIES. http://esid.org/.