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Biomaterials for the Treatment of Tendon Injury

  • Sung Eun Kim
  • Jae Gyoon Kim
  • Kyeongsoon ParkEmail author
Review Article
  • 5 Downloads
Part of the following topical collections:
  1. Molecular Imaging Techniques

Abstract

Background:

Most tendon injuries are occurring from a gradual wearing and tearing of the tendon tissues from overuse. Such injuries are usually seen in sports, exercising, or daily activities that involve a high mechanical load and weight bearing. However, owing to the lack of both cellularity and blood vessels in tendons, the process of tendon repair is slow and inefficient. Although various conservative (non-surgical) and surgical management options are conducted by the clinicians, a gold standard of these approaches does not exist. In this regard, the treatment of tendon injuries is challenging.

Method:

Here, we describe the recent advances of biomaterial-based approaches for the treatment of injured tendons.

Results:

Regenerative medicine is an emerging multidisciplinary research that specializes in the repair of damaged tendon tissues through the delivery of regenerative factors by biomaterials.

Conclusion:

Although current biomaterial-based treatment strategies have shown their potential for tendon healing, future research and clinical applications should focused on finding the optimum combinations of regenerative factors with ideal biomaterials for the repair of tendons.

Keywords

Tendon healing Delivery Biomaterials Regenerative factor Blood vessel 

Notes

Acknowledgements

This research was supported by The Bio & Medical Technology Development Program of the NRF funded by the Korean government, MSIP (NRF-2017M3A9F5030273) and by a Korea University Grant (K1710531).

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical statement

There were no animal experiments carried out for this article.

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Copyright information

© The Korean Tissue Engineering and Regenerative Medicine Society 2019

Authors and Affiliations

  • Sung Eun Kim
    • 1
  • Jae Gyoon Kim
    • 2
  • Kyeongsoon Park
    • 3
    Email author
  1. 1.Department of Orthopedic Surgery and Rare Diseases InstituteKorea University Guro Hospital, Korea University College of MedicineSeoulRepublic of Korea
  2. 2.Department of Orthopedic Surgery, College of MedicineKorea University Ansan Hospital, Korea UniversityAnsan-siRepublic of Korea
  3. 3.Department of Systems Biotechnology, College of Biotechnology and Natural ResourcesChung-Ang UniversityAnseong-siRepublic of Korea

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