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Synthesis of novel spirofused spiropyrrolidine 1,3-indanedione derivatives via 1,3-dipolar cycloaddition reactions

  • Mehdi GhandiEmail author
  • Marziyeh Eshaghi Kenari
  • Alireza Abbasi
Original Paper
  • 17 Downloads

Abstract

The successful synthesis of novel spirofused spiropyrrolidine 1,3-indanedione derivatives using 1,3-dipolar cycloaddition reactions is reported. 1-Benzyl-3,5-bis[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones prepared via Knöevenagel condensation of 1-benzyl-4-piperidinone with aromatic aldehydes underwent a one-pot, three-component reaction with benzylamines and ninhydrin in ethanol to afford the desired products.

Keywords

1,3-Dipolar cycloaddition Spirofused spiropyrrolidine 1 3-Indanedione 1-Benzyl-4-piperidinone 

Notes

Acknowledgements

The authors acknowledge the University of Tehran for financial support of this research.

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Copyright information

© Iranian Chemical Society 2019

Authors and Affiliations

  • Mehdi Ghandi
    • 1
    Email author
  • Marziyeh Eshaghi Kenari
    • 1
  • Alireza Abbasi
    • 1
  1. 1.School of Chemistry, College of ScienceUniversity of TehranTehranIran

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