γ-Aminobutyric acid hydrochloride supported on superparamagnetic γ-Fe2O3@SiO2 as a novel heterogeneous nanocatalyst for the synthesis of 2-amino-5-alkylidene-thiazol-4-one derivatives
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γ-Aminobutyric acid hydrochloride immobilized on superparamagnetic γ-Fe2O3@SiO2 nanoparticles as a novel heterogeneous nanocatalyst was prepared for the first times. It was characterized by several techniques such as XRD, FT-IR, VSM, FE-SEM, EDS, and TGA analysis. The heterogeneous nanocatalyst was used for a convenient, mild, and one-pot efficient three-component preparation of 2-amino-5-alkylidene-thiazol-4-one derivatives under green conditions at room temperature. The main advantage of the method is easily recovery of the stable nanocatalyst by an external magnet from the reaction mixture.
KeywordNano-γ-Fe2O3@SiO2@[CH2)3-(γ-aminobutyric acid.HCl)] Superparamagnetic nanocatalyst 2-Amino-5-alkylidene-thiazol-4-ones Three-component reaction, Green reaction
We are grateful for financial support from the Research Council of University of Sistan and Baluchestan.