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Journal of the Iranian Chemical Society

, Volume 16, Issue 2, pp 209–217 | Cite as

Green synthesis of dissymmetric bisarylidene derivatives of cyclohexanone analogues under ultrasonic conditions

  • Mohammad M. MojtahediEmail author
  • Leila Afshinpoor
  • Fatemeh Karimi
  • M. Saeed Abaee
Original Paper
  • 35 Downloads

Abstract

A new procedure is developed for the synthesis of dissymmetric bisarylidene derivatives of two cyclohexanone analogues. Under mild ultrasonic/organocatalytic conditions, the first aldehyde reacts with the ketone to give the monoarylidene intermediate which subsequently condenses with the second aldehyde upon addition of NaOH/MeOH to the reaction mixture. Both condensations proceed in one pot, and high yields of the corresponding products are obtained in relatively short time periods. It was shown that the method is useful for the synthesis of monoarylidene counterparts as well.

Graphical abstract

Keywords

Green synthesis Dissymmetric bisarylidenes Aldol condensation One-pot reaction Sonochemistry 

Notes

Acknowledgements

We are grateful to the Research Council at CCERCI for the financial support of this work (CCERCI-1395-109).

Supplementary material

13738_2018_1498_MOESM1_ESM.pdf (2.7 mb)
Supplementary material 1 (PDF 2810 KB)

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Copyright information

© Iranian Chemical Society 2018

Authors and Affiliations

  • Mohammad M. Mojtahedi
    • 1
    Email author
  • Leila Afshinpoor
    • 1
  • Fatemeh Karimi
    • 1
  • M. Saeed Abaee
    • 1
  1. 1.Chemistry and Chemical Engineering Research Center of IranTehranIran

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