Cavernous sinus thrombosis in a patient with nephrotic syndrome
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Nephrotic syndrome (NS) is a glomerular disease characterized by altered permeability of the glomerular capillary wall to macromolecules. This results in heavy proteinuria, hypoalbuminemia, hypercholesterolemia, lipiduria, and edema.
This clinical and laboratory syndrome is a life-threatening disease, and is associated with several complications, not only related to the disease itself, but also related to its treatment.
Disease-associated complications include acute kidney injury, chronic kidney disease, cardiovascular disease, negative nitrogen balance, infections, endocrine disorders, and hypercoagulability.
Venous and arterial thromboembolism is a significant complication of NS, occurring in approximately 27% of the patients . This represents an 800% increase relatively to the general population [1, 2]. The pathophysiology of thrombogenesis in NS is not fully understood, and seems to be multifactorial , depending on the etiology (particularly frequent in...
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All the authors have declared no competing interest.
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This article does not contain any studies with human participants or animals performed by any of the authors.
Informed consent was obtained from all individual participants included in the study.
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